WHY FDA BANS NMN as a Natural Supplement - Is It Dangerous?
TLDRThe FDA has announced a ban on NMN as a dietary supplement due to a biotech company investigating it as a drug. NMN, found in foods like avocado and broccoli, helps produce NAD+, linked to aging and chronic diseases. It may slow aging, improve insulin function, and enhance mitochondrial function. Despite the ban, which is due to a potential prescription drug status, not harmful effects, NMN's benefits are reported by users, including looking younger and increased energy. The future availability of NMN as a supplement remains uncertain.
Takeaways
- 🚫 FDA has announced a ban on NMN as a dietary supplement due to ongoing investigations by a biotech company to develop it as a drug.
- 🥑 NMN is a natural ingredient found in small amounts in foods like avocado, cucumber, cabbage, and broccoli, and is related to vitamin B3.
- 🔄 The body can convert vitamin B3 into NMN and has two ways to get NMN into cells: conversion to NR and a direct transporter known as SLC12A8.
- 🌱 A healthy gut is important for the production of NMN, which is suggested by the high presence of the SLC12A8 transporter in the small intestine.
- 💊 NMN helps the body produce more NAD+, a molecule associated with aging and age-related chronic illnesses.
- 📉 As we age, our NMN levels decrease, which can lead to premature aging and chronic diseases.
- 🧪 Studies on mice suggest that NMN supplementation can reduce inflammation, improve insulin production and function, and enhance mitochondrial function.
- 🧠 NMN also supports the protection and regeneration of neurons in the brain and nervous system.
- 🧑🔬 Some individuals, including Professor David Sinclair, have reported looking younger and feeling more energetic with consistent NMN use.
- 🛒 Currently, NMN can be purchased as a supplement on platforms like Amazon, but its future availability as a supplement is uncertain due to the FDA's decision.
- 🔄 The FDA's ban on NMN is not due to safety concerns but because of its potential development as a prescription drug by a biotech company.
Q & A
What has the FDA recently announced regarding NMN supplements?
-The FDA has recently announced that it will ban NMN, a dietary supplement, from the market due to a biotech company investigating NMN as a drug in the next three years.
What is NMN and where can it be found naturally?
-NMN, or Nicotinamide Mononucleotide, is a natural ingredient found in all foods and exists in small amounts in vegetables such as avocado, cucumber, cabbage, and broccoli, and in animal meat mostly as vitamin B3.
How does NMN get into our cells?
-NMN can get into our cells in two ways: it can convert to NR to enter the cell and then reconvert back to NMN, or through a recently discovered transporter known as SLC12A8 that brings NMN directly into the cell.
Why is a healthy gut important for NMN production in the body?
-A healthy gut is important for NMN production because the transporter SLC12A8, which helps bring NMN into cells, exists in the small intestine 100 more times than in other tissues, suggesting a strong link between gut health and NMN levels.
What role does NMN play in the aging process and age-related diseases?
-NMN helps the body produce more NAD+, a molecule associated with the aging process and age-related chronic illnesses like cancer, cardiovascular disease, and neurodegenerative diseases. As we age, our NMN levels and the ability to convert NMN into NAD+ decrease, leading to premature aging and chronic diseases.
What are some potential benefits of NMN supplementation according to studies on mice?
-Studies on mice suggest that NMN supplementation can reduce inflammation in the body, increase insulin production and function, thus helping prevent diabetes, improve mitochondrial function in cells, and protect and regenerate neurons in the brain and nervous system.
Why is the FDA banning NMN as a nutritional supplement?
-The FDA is banning NMN not because it is harmful, but because a biotech company co-founded by Dr. David Sinclair is investigating NMN as a prescription drug, which could potentially lead to a conflict of interest if it remains available as a supplement.
What is the current status of NMN availability as a nutritional supplement?
-As of the script's recording, the FDA has not given any orders to ban the sale of NMN as a nutritional supplement online, but the future availability remains uncertain.
What did the FDA do in a similar situation with NAC as a nutritional supplement?
-In a similar situation with NAC, the FDA banned it as a nutritional supplement due to protests from consumers and nutraceutical companies, but later allowed it to be sold again as a nutritional supplement.
What has been the reported experience of people who have consistently taken NMN?
-People who have consistently taken NMN, including Professor David Sinclair, have reported looking younger, feeling more energetic, and having a better NAD+ level in the blood.
What is the potential impact of the FDA's ban on those using NMN as a nutritional supplement?
-The FDA's ban could limit the accessibility of NMN for those using it as a nutritional supplement, potentially affecting their health and well-being if they have experienced benefits from its use.
Outlines
🚫 FDA's NMN Ban and Its Impact on Aging and Health
The FDA has announced a ban on the dietary supplement NMN (Nicotinamide Mononucleotide) due to a biotech company investigating it as a drug. NMN is a naturally occurring substance found in foods like avocado, cucumber, cabbage, and broccoli, and is crucial for the production of NAD+, a molecule associated with aging and age-related diseases. The supplement has been linked to health benefits such as reduced inflammation, improved insulin production, enhanced mitochondrial function, and neuroprotection. The ban is not due to safety concerns but because the company co-founded by Dr. David Sinclair is researching NMN for prescription drug development. The impact of this decision on consumer access to NMN as a supplement is significant, as many have reported improvements in appearance and energy levels with its use. The future of NMN as a supplement remains uncertain, despite the FDA not having issued a direct ban online sales yet.
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Mindmap
Keywords
💡FDA
💡NMN
💡Dietary Supplements
💡NAD+
💡Aging Process
💡Chronic Diseases
💡Mitochondria
💡SLC12A8
💡NR
💡Biotechnology Company
💡Prescription Drug
Highlights
FDA announces a ban on the dietary supplement NMN due to ongoing investigation by a biotech company.
NMN is a natural ingredient found in foods like avocado, cucumber, cabbage, and broccoli.
NMN is converted from vitamin B3 in the body and plays a role in the production of NAD+.
NMN enters cells through a transporter known as SLC12A8, which is abundant in the small intestine.
NAD+ levels are associated with the aging process and age-related chronic illnesses.
As we age, our NMN levels decrease, affecting our ability to produce NAD+ and potentially leading to premature aging.
Supplementing NMN may slow down the aging process and help prevent chronic diseases.
Studies on mice suggest that NMN can reduce inflammation and improve insulin production and function.
NMN enhances mitochondrial function, which is crucial for cellular energy production.
NMN also aids in the protection and regeneration of neurons in the brain and nervous system.
The effectiveness of NMN in humans is supported by anecdotal evidence and some studies.
People report looking younger, feeling more energetic, and having improved NAD+ levels after taking NMN.
The FDA's ban on NMN is not due to safety concerns but because of its potential as a prescription drug.
The biotech company co-founded by Dr. David Sinclair is investigating NMN to turn it into a prescription drug.
The FDA previously banned NAC as a nutritional supplement but later allowed its sale due to consumer and company protests.
It is uncertain how long NMN will remain available as a nutritional supplement before the FDA's ban takes effect.
Dr. Young's health talk emphasizes the importance of NMN and its potential impact on health and aging.